I'm posting a follow up to my original post with a description of what resolved my issue in case someone comes across this post with a similar problem. The fix I implemented was to change the MSS value for the interface I created for the Wireguard VPN. The following picture shows the MSS setting I changed from a default of "Blank" to 1380. I came to this solution by reading this Netgate blog posting https://www.netgate.com/blog/wireguard-in-pfsense-2-5-performance.html
2ac9afb9-30d8-4137-b455-32e92bc8bf23-image.png
Note: The value in the Description field above does not match the value for the Description field in the tunnel setting in my earlier posting. This is just because I was playing around with the settings when trying to resolve the issue and the value was changed. The discrepancy has no relevance to the solution which was entering 1380 in the MSS field.